Distinguishing the cause of itching, red eyelids is often difficult. P
ruritic, inflamed eyelids can reflect various etiologies and are a com
mon clinical presentation to the office of a dermatologist or ophthalm
ologist. In this article, five of the more common causes of eyelid der
matitis (atopic dermatitis, contact dermatitis, contact urticaria, ros
acea, seborrhea, and psoriasis) are reviewed in detail, with particula
r emphasis on the ocular and periocular features. Clinical clues, hist
orical features, and patch testing in cases of eczematous eyelid derma
titis aid in differential diagnosis. In addition, pathogenesis and tre
atment are reviewed.