Disappearance of migraine during the use of warfarin and of phenprocou
mon has been described in sporadic case reports.(1,2) Treatment with h
eparin has also been associated with a reduction of migrainous headach
es.(3) Recently, the Netherlands Pharmacovigilance Foundation LAREB re
ceived a case report concerning the diminution of migrainous headaches
associated with the use of the vitamin K antagonist, acenocoumarol.