The NK1.1 antigen defines a subset of T cells that produce high titers
of cytokines and express a restricted repertoire of T-cell receptors.
Here, Alain Vicari and Albert Zlotnik discuss the characteristics of
NK1.1(+) T cells that distinguish them from the mainstream CD4(+) help
er or CD8(+) cytotoxic families of T cells. It appears that NK1.1(+) T
cells may play major roles in the regulation of some immune responses
.