SYNTHESIS AND CHARACTERIZATION OF O-6-MODIFIED DEOXYGUANOSINE-CONTAINING OLIGODEOXYRIBONUCLEOTIDES FOR TRIPLE-HELIX FORMATION

Authors
RAYNAUD F ASSELINE U ROIG V THUONG NT
Citation
F. Raynaud et al., SYNTHESIS AND CHARACTERIZATION OF O-6-MODIFIED DEOXYGUANOSINE-CONTAINING OLIGODEOXYRIBONUCLEOTIDES FOR TRIPLE-HELIX FORMATION, Tetrahedron, 52(6), 1996, pp. 2047-2064
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
6
Year of publication
1996
Pages
2047 - 2064
Database
ISI
SICI code
0040-4020(1996)52:6<2047:SACOOD>2.0.ZU;2-0
Abstract
Two new modified deoxyguanosine derivatives linked through their C-6 p osition to a psoralen and an acridine derivative have been synthesized and incorporated into oligonucleotide chains. Difficulties observed d ining the purification of oligonucleotides containing a stretch of G a nd one method used to solve this problem are discussed.