CRYSTALLIZATION OF ADP-RIBOSYL CYCLASE FROM APLYSIA-CALIFORNICA

Authors
PRASAD GS LEVITT DG LEE HC STOUT CD
Citation
Gs. Prasad et al., CRYSTALLIZATION OF ADP-RIBOSYL CYCLASE FROM APLYSIA-CALIFORNICA, Proteins, 24(1), 1996, pp. 138-140
Citations number
19
Categorie Soggetti
Biology
Journal title
Proteins → ACNP
ISSN journal
08873585
Volume
24
Issue
1
Year of publication
1996
Pages
138 - 140
Database
ISI
SICI code
0887-3585(1996)24:1<138:COACFA>2.0.ZU;2-6
Abstract
ADP-ribosyl cyclase synthesizes the secondary messenger cyclic ADP-rib ose from NAD(+). Diffraction quality crystals of the enzyme from ovote stes of Aplysia californica have been obtained. Crystallographic analy sis of this enzyme will yield insight into the mode of binding of the novel cyclic nucleotide and the mechanism by which NAD(+) is cyclized. (C) 1996 Wiley-Liss, Inc.