PROGRESSIVE LUPUS DEMENTIA - 2 CASES WITH OR WITHOUT ANTIPHOSPHOLIPIDANTIBODIES

Two cases of lupus dementia presented many points of particular intere st : 1) the progressive installation of intellectual deterioration, in augural for the first observation; 2) the diagnotic difficulties of ne urolupus with the ARA criteria; 3) the appearance of cerebral magnetic resonance imaging with confluent hypersignals of the periventricular white matter on T2-weighted images; 4) the patholophysiological hypoth eses : vascular disease? immunologic disease? ; 5) clinical improvemen t and SPECT amelioration for the second patient with corticosteroids.