K. Sugimura et al., MRI IN PREDICTING THE RESPONSE OF OVARIAN ENDOMETRIOMAS TO HORMONE-THERAPY, Journal of computer assisted tomography, 20(1), 1996, pp. 145-150
Objective: Our goal was to investigate the usefulness of MRI in predic
ting the response of endometriomas to hormone therapy. Materials and M
ethods: MRI and laparoscopy at the onset of treatment and follow-up MR
I after 6 months of hormone therapy were performed in 21 patients with
49 endometriomas. T1- and T2-weighted images were obtained with a 1.5
T apparatus using a body coil. The lesions were divided into a respon
der group and a nonresponder group according to whether the lesion siz
e decreased by greater than or equal to 50% or not. Results: With MRI,
shading was seen in 25 of 27 lesions (93%) from the nonresponder grou
p, but in only 6 of 22 (27%) from the responder group. Low SI rim was
seen in 59% of the responders and 89% of the nonresponders. Multiplici
ty in 68% of the responders and in 85% of the nonresponders and irregu
larity in 41% of the responders and in 78% of the nonresponders were s
hown. Multiple logistic analysis revealed shading was the most importa
nt factor in prediction of the response to hormone therapy. Conclusion
: Shading was an important sign in evaluating the response of endometr
iomas to hormone therapy. MRI may assist in selecting the appropriate
therapy for endometriomas.