Mc. Neri et al., PREVALENCE OF HELICOBACTER-PYLORI INFECTION IN ELDERLY INPATIENTS ANDIN INSTITUTIONALIZED OLD-PEOPLE - CORRELATION WITH NUTRITIONAL-STATUS, Age and ageing, 25(1), 1996, pp. 17-21
Helicobacter pylori plays an important role in the aetiology and devel
opment of peptic ulcer disease. The prevalence of H. pylori infection
increases with age, and is influenced by low socioeconomic status and
poor hygiene owing to person-to-person transmission of the organism by
the oral-faecal route. The aim of this study was to investigate the p
revalence of H. pylori infection, detected serologically, in elderly p
atients admitted to a geriatric rehabilitation ward and in a sample of
institutionalized old subjects. Nutritional status was also evaluated
in order to examine its relation to H. pylori infection. The overall
prevalence of H. pylori infection was 70.8%, the prevalence in hospita
lized patients being 72.9% and in institutionalized subjects 68.7%. No
significant correlation was observed between anti-H. pylori IgG level
s and either age or length of stay in the institution. We found no dif
ference between H. pylori positive and negative patients as regards th
eir self-sufficiency and cognitive functions. The prevalence of anti-H
. pylori antibodies in the serum was not related to blood variables (i
ncluding nutritional indices), history of drug consumption (in particu
lar nonsteroidal anti-inflammatory drugs), dyspeptic symptoms, or alco
hol and smoking habits.