T. Kossmann et al., PENETRATION OF CEFUROXIME INTO THE CEREBROSPINAL-FLUID OF PATIENTS WITH TRAUMATIC BRAIN INJURY, Journal of antimicrobial chemotherapy, 37(1), 1996, pp. 161-167
Cefuroxime levels were measured in cerebrospinal fluid (CSF) and serum
of four patients with traumatic brain injury following the implantati
on of intraventricular catheters. The levels ranged from 0.15 to 2.03
mu g/mL in CSF and from 1.8 to 66.9 mu g/mL in serum. No ventriculosto
my related infections were detected.