LIPID PEROXIDE METABOLISM IN OOPHORECTOMISED RATS

Authors
SREELATHAKUMARI KT MENON VP LEELAMMA S
Citation
Kt. Sreelathakumari et al., LIPID PEROXIDE METABOLISM IN OOPHORECTOMISED RATS, Indian journal of medical research. Section B: Biomedical research other than infectious diseases, 98, 1993, pp. 305-308
Citations number
16
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Indian journal of medical research. Section B: Biomedical research other than infectious diseases → ACNP
ISSN journal
09709568
Volume
98
Year of publication
1993
Pages
305 - 308
Database
ISI
SICI code
0019-5340(1993)98:<305:LPMIOR>2.0.ZU;2-8
Abstract
The effect of bilateral oophorectomy and the administration of beta-es tradiol on lipid peroxide metabolism were studied in rats. The lipid p eroxide levels were measured in the oophorectomised and the estradiol administered animals. The level of lipid peroxide increased in the liv er in oophorectomised animals, whereas no change was observed in the h eart. The activity of antiperoxidative enzymes superoxide dismutase an d catalase was found to be decreased in both the liver and the heart. Oophorectomy resulted an the elevation of serum ceruloplasmin. Adminis tration of estradiol to oophorectomised rats restored the altered lipi d peroxide levels.