C. Ballard et al., THE PREVALENCE, ASSOCIATIONS AND SYMPTOMS OF DEPRESSION AMONGST DEMENTIA SUFFERERS, Journal of affective disorders, 36(3-4), 1996, pp. 135-144
Objective: To examine the prevalence rates of RDC major and RDC minor
depression in dementia sufferers, to compare the prevalence rates and
symptoms of depression between different dementias and to look at the
associations of RDC major depression. Design: Case control. Setting: R
eferrals to clinical services. Subjects: 124 patients with DSM-III-R d
ementia. Measures: The patients were assessed using the GMS/HAS packag
e and the Cornell Depression Scale. Depression was diagnosed according
to RDC criteria. Results: 25.0% of patients had RDC major depression
and 27.4% had RDC minor depression. Major depression occurred signific
antly more often and was significantly more severe in patients with va
scular dementia than patients with Alzheimer's disease. Severe visual
impairment was significantly associated with RDC major depression in A
lzheimer's disease and physical health problems were significantly ass
ociated with depression in vascular dementia, Most symptoms of depress
ion including suicidal thoughts were common. Conclusions: Major depres
sion is more common and more severe in patients with vascular dementia
. The associations of depression may be different in these patients.