THE CLINICAL-SIGNIFICANCE OF AN AUTOIMMUNE-RESPONSE AGAINST GLUTAMIC-ACID DECARBOXYLASE

Authors
ELLIS TM ATKINSON MA
Citation
Tm. Ellis et Ma. Atkinson, THE CLINICAL-SIGNIFICANCE OF AN AUTOIMMUNE-RESPONSE AGAINST GLUTAMIC-ACID DECARBOXYLASE, Nature medicine, 2(2), 1996, pp. 148-153
Citations number
30
Categorie Soggetti
Medicine, Research & Experimental",Biology,"Cell Biology
Journal title
Nature medicine → ACNP
ISSN journal
10788956
Volume
2
Issue
2
Year of publication
1996
Pages
148 - 153
Database
ISI
SICI code
1078-8956(1996)2:2<148:TCOAAA>2.0.ZU;2-7
Abstract
Glutamic acid decarboxylase is attracting much interest because of its putative involvement in two clinical disorders: stiff-man syndrome an d insulin-dependent diabetes. Here we discuss the clinical significanc e of an autoimmune response against GAD and consider how such informat ion may help identify the disease mechanisms of these disorders.