NODULAR REGENERATIVE HYPERPLASIA OF THE LIVER - DESCRIPTION OF 2 CASES

Nodular regenerative hyperplasia (NRH) of the liver is a condition of unknown origin, rarely occurring in children, usually accidentally dis covered, described in association with a variety of clinical condition s and drugs. Confusion with other types of hepatic masses may pose a p roblem and for this reason NRH is considered a ''tumor-like lesion.'' Histologically it consists of single or multiple regenerative foci. He patic failure and rupture of the liver have been rarely described as c omplications in adults, and not in children, and malignant transformat ion has not been demonstrated. Neither surgical removal nor other trea tment is needed. These features are described as they were found in tw o patients we encountered. (C) 1996 Wiley-Liss, Inc.