Jh. Brandenburg et al., VOCAL CORD INJECTION WITH AUTOGENOUS FAT - A LONG-TERM MAGNETIC-RESONANCE-IMAGING EVALUATION, The Laryngoscope, 106(2), 1996, pp. 174-180
Since 1987, the senior author has injected autogenous fat into paralyz
ed or atrophic vocal cords as an alternative to alloplastic substances
for vocal cord augmentation and medialization. To determine the fate
of the injected autogenous fat, the injected vocal cords of 10 patient
s were evaluated by laryngeal magnetic resonance imaging (MRI) in the
sagittal, coronal, and axial planes. Imaging studies were performed as
early as 17 hours after surgery to as long as 31 months after fat inj
ection. In 9 patients, identification of a fat signal within the previ
ously injected vocal cords was observed (including the 31-month postop
erative follow-up). In 1 patient, no fat signal was identified 13 mont
hs after surgery, but the vocal cord was noted to have a bulging enlar
ged contour. The results of this imaging study provide further evidenc
e that autogenous fat, which has not been damaged during harvesting or
microinjection, can survive transplantation into the vocal cord. The
bulk of the vocal cord is maintained by microlipocytes and fibrous con
nective tissue, both of which replace the damaged fat cells that are g
radually being reabsorbed.