S. Passero et D. Nuti, AUDITORY AND VESTIBULAR SYSTEM FINDINGS IN PATIENTS WITH VERTEBROBASILAR DOLICHOECTASIA, Acta neurologica Scandinavica, 93(1), 1996, pp. 50-55
Impairment of the auditory-vestibular system has been reported in pati
ents with vertebrobasilar dolichoectasia (VBD), but little is known ab
out the underlying cause of the symptoms. Auditory testing (pure tone
audiometry, auditory brain stem response and stapedius reflex) and ves
tibular tests (assessment of nystagmus, eye tracking tests, caloric te
st and rotational test) were performed in 23 patients with auditory-ve
stibular symptoms and/or cranial nerve impairment associated with VBD.
Specific evidence of auditory and/or vestibular system impairment was
observed in 19 cases (83%). Among patients with abnormal test finding
s, 47% had evidence suggesting peripheral impairment, 16%, evidence su
ggesting central dysfunction, and 37% evidence suggesting both periphe
ral and central dysfunction. Although compression of the vestibulococh
lear nerve plays an important role in the genesis of the auditory-vest
ibular dysfunction in patients with VBD, mechanism such as brain stem-
cerebellar ischemia and impaired blood supply to the vestibular labyri
nth may be just as important.