CONTENT AND SEX DIFFERENCE OF THE FRANK LEAD SIGNAL-AVERAGED ECG IN APOPULATION WITH SIGNIFICANT CORONARY-ARTERY-DISEASE - COMPARISON WITHCONCURRENT 12-LEAD ECG MORPHOLOGY

The 12-lead electrocardiogram (ECG) and a 100-beat signal-averaged Fra nk lead EGG (SAEGG) at a sampling rate of 1,000 Hz and with 16-bit res olution were recorded from 52 women and 256 men with significant coron ary artery disease presenting for coronary artery revascularization. T he QRS portion of each Frank lead was digitally filtered in four bandw idths: 0-10, 10-60, 60-150, and 150-250 Hz. The root-mean-square (RMS) voltage of each filtered signal was calculated as an absolute value a nd normalized as a percentage of the sum of the four filters, creating 27 variables. Three groups were formed using the presenting 12-lead E GG: N-EGG, ST-EGG, and MI-EGG. Despite variation in 12-lead morphology , concordance was dominant in the RMS values of the SAEGG in sex compa risons within and between groups. There was significant sex difference of the RMS values in 6 of the 15 absolute RMS variables within the th ree groups. Women had no significant between-group difference, and men had a significant between-group differences in five absolute values a nd one normalized RMS value. P was considered significant at <.05.