In this study, postural stability was measured with a microcomputer-ba
sed force platform as an indirect assessment of central nervous system
effect in 28 sewer workers (age range 23.4 to 64.5 years, standard de
viation of 8.7 years). All workers performed four 30-second postural s
way tests. The organic-solvent exposure was measured by a photoionizat
ion detector: The photo-ionization detector was calibrated to measure
volatile organic solvents in total benzene equivalence, and concentrat
ions were measured in various parts of the plant. The mean exposure wa
s .32 parts per million (ppm) benzene equivalent (range of .02 to .95
ppm, standard deviation .19 ppm). Based on a covariate adjusted linear
multiple-regression model, a statistically significant (p < .05) posi
tive correlation was demonstrated between postural sway and organic-so
lvent exposure. These workers also had increased postural sway compare
d with a nonexposed population. The statistically significant correlat
ion between postural sway determinations and organic-solvent exposure
was surprising given the very low exposures measured. It is possible t
hat the organic-solvent exposure might not be the causative agent, but
rather that the solvents themselves correlate with some other causati
ve exposure, ie, total volatile organics as implicated in the cause of
sick-building syndrome.