Magnetic resonance (MR) imaging has emerged as the preferred modality
for the imaging evaluation of musculoskeletal tumors. Although there i
s general agreement on the value of MR in diagnosis and staging, the u
se of intravenous contrast in the evaluation of musculoskeletal lesion
s remains controversial. The purpose of this review is to highlight th
ese controversies, to put them in perspective, and to suggest recommen
dations for the use of gadopentetate dimeglumine. The following specif
ic areas will be addressed: (a) evaluation of soft-tissue tumors, (b)
diagnosis of low-grade chondrosarcoma and the use of contrast material
in identification of intraosseous metastases, (c) monitoring response
to chemotherapy, (d) evaluation for local recurrence after surgery an
d/or radiation therapy, and (e) selection of biopsy site.