HYPOPIGMENTED MYCOSIS-FUNGOIDES

Introduction, Isolated areas of hypopigmented skin can be a manifestat ion of mycosis fungoides. This is a rare clinical form with a particul ar clinical course and histology which has been described only in blac k subjects. Case report. Over a 10-year period, a 28-year-old woman fr om Mall developed non-infiltrated hypopigmented and discretely squamou s macules involving the entire body. The diagnosis of mycosis fungoide s was made on pathology evidence of epidermotropic lymphocyte infiltra tion with a few small nests. PUVA led to rapid regression of the lesio ns. Discussion, Hypopigmented mycosis fungoides has been described in young black subjects (mean age 19 years). The diagnosis is usually mad e late because benign skin affection is usually the first diagnosis (p ityriasis alba, pityriasis versicolor). The pathogenesis of these hypo pigmented lesions is not known. PUVA appears to be effective in most c ases.