The case of a 67-year-old Japanese woman with leiomyoma arising from t
he lesser omentum is reported herein. Although the patient had no abdo
minal symptoms, findings of a routine abdominal ultrasound examination
suggested a mass between the stomach and the lateral segment of the l
iver. Subsequent magnetic resonance imaging (MRI) demonstrated a 6-cm
well-encapsulated tumor in the lesser omentum, and this was confirmed
intraoperatively. Resection of the tumor was performed without any oth
er procedure and the histological diagnosis was confirmed as leiomyoma
. The patient has been well for the 6 months since her operation. To o
ur knowledge, this is the first report in the English literature of le
iomyoma arising from the lesser omentum.