BIOACTIVITIES AND STRUCTURAL STUDIES OF WITHANOLIDES FROM WITHANIA-SOMNIFERA

Authors
JAMAL SA QURESHI S ALI SN CHOUDHARY MI",ATTAURRAHMAN
Citation
Sa. Jamal et al., BIOACTIVITIES AND STRUCTURAL STUDIES OF WITHANOLIDES FROM WITHANIA-SOMNIFERA, Himia geterocikliceskih soedinenij, (9), 1995, pp. 1200-1213
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Himia geterocikliceskih soedinenij → ACNP
ISSN journal
01326244
Issue
9
Year of publication
1995
Pages
1200 - 1213
Database
ISI
SICI code
0132-6244(1995):9<1200:BASSOW>2.0.ZU;2-7
Abstract
Four bioactive withanolides, withalactone (1) withaoxylactone (2), qur esimine-A (4 beta-hydroxy, 3 beta-methoxy-5 beta,6 beta-epoxy-(22R)-wi tha-24-enolide) (3) and quresimine-B (4 beta, 27-dihydroxy-3 beta-meth oxy-5 beta,6 beta-epoxy-(22R)-witha-24-enolide (4) have been isolated from the herbs of Withania somnifera, Dunal (Solanaceae). The elucidat ion of their structures is based on extensive spectroscopic studies, s uch as H-1-NMR, COSY-45 degrees, HMBC, HMQC, HOHAHA, E.I., FAB (+ ve) and HR MS etc.