Jw. Lee et al., ONE-POT SYNTHESIS OF OXAZOLIDINONES BY TOSYLATION OR MESYLATION OF N-BOC-BETA-AMINO ALCOHOLS, Synthetic communications, 26(1), 1996, pp. 83-88
Oxazolidinones have been synthesized from the reaction of N-Boc deriva
tives of beta-amino alcohols with TsCl or MsCl. Basic reaction conditi
on is not necessary to the formation of oxazolidinone from the tosylat
ed intermediate. On the other hand, oxazolidinone was produced from N-
Boc derivative of beta-amino alcohol under NaH.