The surgical management of secondary peritonitis is based on the follo
wing control of the pathologic process causing the bacterial contamina
tion, peritoneal toilet and prevention of recurrent infection. Gastric
and small bowel perforations are generally treated by simple suture o
r resection with primary anastomosis. Peritonitis secondary to large b
owel perforation results in 15 to 60% mortality depending on the etiol
ogy of the perforation. Some studies have questioned the surgical dogm
a which forbids primary anastomosis after perforated sigmoid diverticu
litis or traumatic colonic perforation. The interest for laparoscopy i
n peritonitis is based on the theorical advantage of reducing the morb
idity of midline incisions of the contaminated abdomen. Laparoscopy se
ems to be admitted as treatment for biliary peritonitis (acute cholecy
stitis). The indication for laparoscopic treatment of appendicular per
itonitis or duodenal ulcer perforation however has still to be validat
ed. Peroperative peritoneal lavage with isotonic solutions, with or wi
thout antiseptics or antibiotics, as well as the systematic and comple
te peritoneal debridment have not shown any advantage in terms of redu
ction of intra peritoneal abscesses or reduction of mortality. In adva
nced peritonitis, the utility of postoperative peritoneal lavage, plan
ned relaparotomies as well as laparostomy has yet to be established. F
uture prospective evaluations of surgical techniques for the treatment
of secondary peritonitis should include a severity score, preferably
based on the preoperative APACHE II score, rather than on peroperative
findings.