A 40-year-old man had new onset of hemoptysis and hematemesis, Broncho
scopy revealed red, inflamed mucosa with apparent rich blood supply in
the left primary bronchus. Computed tomography revealed calcified sub
carinal lymph nodes with a small extension into the left primary bronc
hus, Shortly after admission, the patient had an episode of gastrointe
stinal bleeding, Esophagogastroduodenoscopy showed a lesion in the pos
terior wall of the esophagus, 12 cm from the upper incisors. During ex
ploratory thoracotomy, a single piece of irregular-shaped tan tissue m
easuring 3.5 x 2.5 x 2.0 cm and engulfing the esophagus, carina, and l
eft primary bronchus was dissected, A single stonelike mass,or broncho
lith, was found to involve both the trachea and the esophagus. Microsc
opic examination showed multiple caseating granulomas with surrounding
lymphoid tissue and germinal centers. During 12 months of follow-up,
the patient has remained asymptomatic, The chronic inflammation in thi
s case suggested granulomatous mediastinitis, a rare disease whose mas
s-like effects may contribute to structural compression. The trachea a
nd esophagus are rarely involved. Tuberculosis and histoplasmosis are
thought to be the two most common causes of granulomatous mediastiniti
s, Chronic inflammation leading to calcification and broncholith may i
nvade bronchial lumen or esophageal wall, causing life-threatening hem
orrhage and necessitating prompt surgical intervention.