CORRELATION OF OXIDATION POTENTIAL AND TOXICITY IN THIOBENZAMIDES

Authors
COPPOLA GM ANJARIA H DAMON RE
Citation
Gm. Coppola et al., CORRELATION OF OXIDATION POTENTIAL AND TOXICITY IN THIOBENZAMIDES, Bioorganic & medicinal chemistry letters, 6(2), 1996, pp. 139-142
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
2
Year of publication
1996
Pages
139 - 142
Database
ISI
SICI code
0960-894X(1996)6:2<139:COOPAT>2.0.ZU;2-V
Abstract
The oxidation potentials of a series of 4-substituted thiobenzamides ( 1) were measured by linear sweep voltammetry. When compared with the k nown toxicological values for these compounds it was found that there is a direct correlation between oxidation potential and toxicity.