EARLY EFFECTS OF C-60 ADMINISTRATION IN SWISS MICE - A PRELIMINARY ACCOUNT FOR IN-VIVO C-60 TOXICITY

Authors
MOUSSA F TRIVIN F CEOLIN R HADCHOUEL M SIZARET PY GREUGNY V FABRE C RASSAT A SZWARC H
Citation
F. Moussa et al., EARLY EFFECTS OF C-60 ADMINISTRATION IN SWISS MICE - A PRELIMINARY ACCOUNT FOR IN-VIVO C-60 TOXICITY, Fullerene science and technology, 4(1), 1996, pp. 21-29
Citations number
10
Categorie Soggetti
Chemistry Physical","Physics, Atomic, Molecular & Chemical","Material Science
Journal title
Fullerene science and technology → ACNP
ISSN journal
1064122X
Volume
4
Issue
1
Year of publication
1996
Pages
21 - 29
Database
ISI
SICI code
1064-122X(1996)4:1<21:EEOCAI>2.0.ZU;2-0
Abstract
High amounts of micronized C-60 have been injected intraperitoneally i nto Swiss mice. Until the fourteenth day, they were still alive withou t any behaviour trouble. C-60 was well absorbed, and found localized i n spleen and liver. Inside the liver, C-60 was detected in Kupffer cel ls and hepatocytes. But the main result is the induced hypertrophy of the perisinusoidal cells, where C-60 preferentially accumulates.