RELATION BETWEEN HEMATOLOGICAL RECOVERY AND NUMBER OF TRANSPLANTED MONONUCLEAR-CELLS IN PATIENTS AFTER HIGH-DOSE CHEMOTHERAPY WITH PERIPHERAL-BLOOD STEM-CELL RESCUE

Authors
KOUMAKIS G FILIS J VASSILOMANOLAKIS M PAPANASTASIOU K HAJICHRISTOU H BARBOUNIS V STAMATELLOU M EFREMIDIS AP
Citation
G. Koumakis et al., RELATION BETWEEN HEMATOLOGICAL RECOVERY AND NUMBER OF TRANSPLANTED MONONUCLEAR-CELLS IN PATIENTS AFTER HIGH-DOSE CHEMOTHERAPY WITH PERIPHERAL-BLOOD STEM-CELL RESCUE, Blood cells, molecules, & diseases, 21(24), 1995, pp. 235-238
Citations number
8
Categorie Soggetti
Hematology
Journal title
Blood cells, molecules, & diseases → ACNP
ISSN journal
10799796
Volume
21
Issue
24
Year of publication
1995
Pages
235 - 238
Database
ISI
SICI code
1079-9796(1995)21:24<235:RBHRAN>2.0.ZU;2-X
Abstract
The aim of the study is to investigate the relation between the hemato logical recovery in patients after high dose chemotherapy and peripher al blood stem cell (PBSC) rescue and the number of reinfused previousl y collected stem cells assessed by the number of mononuclear cells (MN Cs), CFU-GMs and CD34(+) cells in the harvest. Forty nine patients mob ilized with different techniques were transplanted, Our data indicate that the number of reinfused MNCs and CFU-GMS has a statistical signif icant relationship with the duration of leukopenia and thrombocytopeni a following high dose chemotherapy and PBSC rescue in patients with va rious malignancies.