DISORDERS OF HIGHER CORTICAL FUNCTIONS IN HYPOTHALAMIC-LESIONS AND THEIR REFLECTION IN EEG - COMPUTER-ANALYSIS

In order to reveal correlations between disturbances in higher cortica l functions and characteristics of electrical activity 70 patients wit h pathological foci in the hypothalamic regions were examined using co mputer data processing. Destruction of the normal intercentral relatio ns between EEG rhythms develops under the influence of the hypothalami c focus, The process builds up with the aggravation of cortical disord ers (mnestic, emotional-affective, consciousness oppression with sleep inversion). General decrease of EEG coherence is observed with the hi ghest destruction of correlations in the frontal cortical areas, The s tructure of high-frequency alpha-rhythm becomes deranged even in sligh t cortical disorders, its coherence decreases predominantly in the fro ntal cortical areas, With intensification of the pathological process in the focus, the stage of delta-rhythm coherence increase is observed and at the background of general destruction of correlations new, pat hological intercentral relations develop. Using a BRAINLOC computer te chnique <<sources>> of the delta- and theta-activity have been localiz ed in the medio-basal brain regions, The area of localization is speci fic for hypothalamic lesions, The <<source>> is mostly expressed in th e slightest pathology of higher cortical functions, With aggravation o f the process in the hypothalamic pathological focus and further deran gement in the cortical functions expression of the <<sources>> reduces up to their complete disintegration in coma.