SPATIOTEMPORAL ORGANIZATION OF MEMBRANE-S YNAPTIC MODIFICATIONS AND MOMENTARY TOPOGRAMS OF SLOW VARIATIONS OF CORTICAL POTENTIALS DURING LEARNING

This paper deals with an actual problem of specificity of organization of different stages of a conditioned reflex (CR). We suggest to consi der this problem at the level of membrane-synaptic modifications compa ring them with the indices of changes in the spatial organization of s low potentials in the cortex. The definite sequence of involvement of cellular mechanisms has been shown which can determine different featu res of the spatial organization of cortical slow potentials. Changes i n cellular excitability of cortical neurons are probably connected wit h the variations of the general level of momentary electroencephalotop ograms and, correspondingly, with the level of general spatial synchro nization. Involvement of excitatory and inhibitory synaptic connection s (with the efficiency corresponding to CR stages) determines the form ation of electroencephalotopogram reliefs. Indices of both levels depe nd of hypothalamic effects on the cortex.