Quality assurance and inclusion of prospective evaluation of costs of
treatment in phase 3 and 4 pharmaceutical trials are becoming increasi
ngly important. Not only high technology applications have to be inves
tigated, but also relatively cheap but very common strategies for diag
nostic work up and therapy. This may yield major savings. We are at th
e beginning of an era in which waste of resources may be reduced by sc
ientific analysis with improvement in patient care and teaching achiev
ed as a result.