TANDOSPIRONE

Tandospirone is a new addition to the azapirone class of anxiolytics, which may be useful for the long term treatment of anxiety and depress ive neuroses. It is a serotonin (5-hydroxytryptamine; 5-HT)(1A) recept or agonist that has anxiolytic effects. Unlike benzodiazepines, the an xiolytic and antidepressant effects of tandospirone can be separated f rom the sedative, anticonvulsant and muscle relaxant effects. The abus e potential of tandospirone appears to be lower than that of benzodiaz epines. Tandospirone has anxiolytic effects similar to those of diazep am in patients with various different neuroses.