CREATION AND STUDY OF IMMUNOGLOBULIN TO E BOLA FEVER

Authors
BORISEVICH IV MIKHAILOV VV KRASNYANSKY VP GRADOBOYEV VN LEBEDINSKAYA YV POTRYVAYEVA NV TIMANKOVA GD
Citation
Iv. Borisevich et al., CREATION AND STUDY OF IMMUNOGLOBULIN TO E BOLA FEVER, Voprosy virusologii, 40(6), 1995, pp. 270-273
Citations number
19
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
40
Issue
6
Year of publication
1995
Pages
270 - 273
Database
ISI
SICI code
0507-4088(1995)40:6<270:CASOIT>2.0.ZU;2-F
Abstract
Immunoglobulin to Ebola fever has been for the first time prepared fro m hyperimmune equine blood sera by alcohol fractionation after Cohn. P reclinical study of the physicochemical and immunobiological propertie s of immunoglobulin showed that it protects up to 100% Papio. hamadrya s infected intramuscularly at doses of 110 to 29 LD(50) Ebola virus. S cheme for the use of Ebola immunoglobulin has been experimentally vali dated.