Objective: To determine the characteristics of a new cocoa-based edibl
e spacer device for the delivery of aerosol bronchodilator. Design: In
vitro comparison of two spacer devices (standard and edible) and dete
rmination of bronchodilator response using the edible spacer. Setting:
A university children's hospital in Western Australia. Subjects: Two
volunteers with moderate asthma. Results: Compared with a standard spa
cer, the edible spacer delivered significantly more bronchodilator in
droplets of a size likely to enter the respiratory tract. A significan
t bronchodilator response occurred in two out of two subjects when sal
butamol was inhaled orally via the chocolate spacer. No significant br
onchodilator response occurred in either subject when the spacer was e
aten at the end of the study. Conclusion: The chocolate spacer used in
this study is a suitable device to deliver salbutamol by inhalation.
However, there may be potential drawbacks of weight gain in some patie
nts and meltdown in hot climates.