THE CHOCUHALER - SWEET DELIVERANCE IN ASTHMA MANAGEMENT

Citation
Mj. Hayden et al., THE CHOCUHALER - SWEET DELIVERANCE IN ASTHMA MANAGEMENT, Medical journal of Australia, 163(11-12), 1995, pp. 587-588
Citations number
5
Categorie Soggetti
Medicine, General & Internal
ISSN journal
0025729X
Volume
163
Issue
11-12
Year of publication
1995
Pages
587 - 588
Database
ISI
SICI code
0025-729X(1995)163:11-12<587:TC-SDI>2.0.ZU;2-H
Abstract
Objective: To determine the characteristics of a new cocoa-based edibl e spacer device for the delivery of aerosol bronchodilator. Design: In vitro comparison of two spacer devices (standard and edible) and dete rmination of bronchodilator response using the edible spacer. Setting: A university children's hospital in Western Australia. Subjects: Two volunteers with moderate asthma. Results: Compared with a standard spa cer, the edible spacer delivered significantly more bronchodilator in droplets of a size likely to enter the respiratory tract. A significan t bronchodilator response occurred in two out of two subjects when sal butamol was inhaled orally via the chocolate spacer. No significant br onchodilator response occurred in either subject when the spacer was e aten at the end of the study. Conclusion: The chocolate spacer used in this study is a suitable device to deliver salbutamol by inhalation. However, there may be potential drawbacks of weight gain in some patie nts and meltdown in hot climates.