Since its introduction in 1985, the new fluoroquinolone antibiotic ofl
oxacin has gained widespread use, and much information has accumulated
about its possible adverse effects, Skin reactions have been uncommon
, and there have been very few reports about hypersensitivity vasculit
is directly related to ofloxacin, The authors report such a case, in w
hich the patient needed plastic surgery because of severe vasculitis i
n both legs.