POTENT ALPHA-KETOCARBONYL AND BORONIC ESTER DERIVED INHIBITORS OF PROTEASOME

Authors
IQBAL M CHATTERJEE S KAUER JC MALLAMO JP MESSINA PA REIBOLDT A SIMAN R
Citation
M. Iqbal et al., POTENT ALPHA-KETOCARBONYL AND BORONIC ESTER DERIVED INHIBITORS OF PROTEASOME, Bioorganic & medicinal chemistry letters, 6(3), 1996, pp. 287-290
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
3
Year of publication
1996
Pages
287 - 290
Database
ISI
SICI code
0960-894X(1996)6:3<287:PAABED>2.0.ZU;2-Y
Abstract
Potent and selective alpha-ketocarbonyl (8a-b) and boronic ester (11) derived inhibitors of the chymotrypsin-like activity of proteasome, fi rst member of a newly identified class of threonine proteases, are des cribed.