CIRCADIAN VARIATION OF NITRIC-OXIDE SYNTHASE ACTIVITY AND CYTOSOLIC PROTEIN-LEVELS IN RAT-BRAIN

Authors
AYERS NA KAPAS L KRUEGER JM
Citation
Na. Ayers et al., CIRCADIAN VARIATION OF NITRIC-OXIDE SYNTHASE ACTIVITY AND CYTOSOLIC PROTEIN-LEVELS IN RAT-BRAIN, Brain research, 707(1), 1996, pp. 127-130
Citations number
25
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
707
Issue
1
Year of publication
1996
Pages
127 - 130
Database
ISI
SICI code
0006-8993(1996)707:1<127:CVONSA>2.0.ZU;2-B
Abstract
The circadian variation of nitric oxide synthase (NOS) activity and cy tosolic protein content in the cerebellum, brainstem, hypothalamus, hi ppocampus, and the remainder of the brain were studied in rats. Both N OS activity and cytosolic protein concentrations were the highest duri ng the dark period and lowest in the light period. Hypothalamic NOS ac tivity exhibited the most pronounced change in activity with time incr easing by similar to 120% from mid-light to mid-dark.