KLEINE-LEVIN SYNDROME IN A BOY WITH PRADER-WILLI-SYNDROME

A 9 1/2-year-old Taiwanese boy with Prader-Willi syndrome had the foll owing characteristics: difficulties with sucking, feeding and hypotoni a during infancy, a dysmorphic face (triangular mouth, high arched pal ate, almond-shaped eyes and large head circumference with a relatively narrow bifrontal diameter), borderline intelligence, hypogonadism, hy perphagia, skin picking and truncal obesity. The boy experienced two h ypersomnia episodes, at age 8 and 9 years, with both episodes lasting for 10 days. During the two episodes, he was found to have an exacerba ted case of hyperphagia, pica., poor emotional control, stereotyped sp eech and agitated behavior upon awakening. After each episode, the boy had complete remission. Our findings show that the two episodes are c ompatible with the Kleine-Levin syndrome. The relationship between the two syndromes, the Prader-Willi syndrome and the Kleine-Levin syndrom e, deserves further study.