A retrospective analysis of 100 children followed at Children's Memori
al Hospital, Chicago, who underwent surgery for a spinal lipoma was pe
rformed. The mean follow-up was 5 years. We found that an operation pe
rformed during the Ist year of life with the goal of untethering the s
pinal cord and debulking the spinal lipoma was safe and effective, whe
reas a cosmetic (nonuntethering) procedure always led to delayed posto
perative deterioration (symptomatic tethered cord). Of the infants tha
t presented with motor, urologic or orthopedic symptoms, 39% improved,
58% stabilized, while 3% worsened as a result of surgery. No asymptom
atic infant deteriorated postoperatively and 93% of these children rem
ained symptom-free at follow-up (mean follow-up was 44 months). The ov
erall outcome of infants after untethering procedures in this study wa
s significantly better than the natural history of spinal lipomas. Sev
eral risk factors were identified that may predispose children to dela
yed postoperative deterioration: an initial cosmetic procedure; the pr
esence of preoperative symptoms, and the presence of a lipomyelomening
ocele.