SIMPLIFIED ANALYSIS OF CHROMATOGRAPHIC-COLUMN DYNAMICS

Citation
M. Giona et al., SIMPLIFIED ANALYSIS OF CHROMATOGRAPHIC-COLUMN DYNAMICS, Chemical Engineering Science, 49(4), 1994, pp. 541-547
Citations number
21
Categorie Soggetti
Engineering, Chemical
ISSN journal
00092509
Volume
49
Issue
4
Year of publication
1994
Pages
541 - 547
Database
ISI
SICI code
0009-2509(1994)49:4<541:SAOCD>2.0.ZU;2-G
Abstract
A simplified analysis of chromatographic-column dynamics based on a si milarity equation (found experimentally) for outlet chromatograms of s ize-exclusion columns is developed. A theoretical explanation of the s imilarity equations is developed in the case of a convection-diffusion model. A criterion for validating the similarity results is proposed. As a corollary of the above analysis, an integral method for evaluati ng the variance is proposed.