Jm. Bryan et al., COMPARISON OF INSIDE-OUT AND OUTSIDE-IN INTERFERENCE SCREW FIXATION FOR ANTERIOR CRUCIATE LIGAMENT SURGERY IN A BOVINE KNEE, Arthroscopy, 12(1), 1996, pp. 76-81
Despite numerous advances in graft fixation with anterior cruciate, li
gament (ACL) reconstruction, few studies have compared the fixation st
rength of interference screws placed ''outside-in'' and from ''inside-
out'' techniques. To compare techniques, a bovine model was designed t
o fail at the femoral tunnel bone-screw interface. Twenty-four fresh b
ovine knees were stripped of all soft tissues except the ACL. The nati
ve ACL was loaded the failure at a strain rate of 50 cm/min with the k
nee flexed 45 degrees. One standardized femoral tunnel was created on
all specimens. A 3/32-inch guide pin was drilled into the center of th
e ACL femoral origin and overreamed with an Il-mm reamer from inside-o
ut until the lateral cortex was reamed, Consistently sized patellar bo
ne blocks were created (8 X 5 X 25 mm) with an 8-mm tendon width, The
bone blocks were randomized to an ''inside-out'' (group 1) and ''outsi
de-in'' (group 2) technique. Bone blocks were secured with a 7 X 25 in
terference screw. Specimens were mounted with the femoral tunnel and b
one block aligned parallel to the tensile force and strained to failur
e at 50 cm/min. Failure of the native bovine ACL occurred at a mean of
2,304 N (SD +/- 472 N; n = 24). The mode of failure for group 1 was 9
of 13 at the bone-screw interface and 4 of 13 interligamentous failur
es. The mode of failure for group 2 was 7 of 11 at the bone-screw inte
rface, 3 of 11 interligamentous, and 1 bone block failure. The mean lo
ad to failure for group 1 was 1,151 N (SD +/- 320 N, n = 13) including
the-four ligamentous failures and 1,143 N (SD +/- 306 N, n = 9) exclu
ding the ligamentous failures. The mean load to failure for group 2 wa
s 1,017 N (SD +/- 262 N, n = 11), including all specimens and 843 N (S
D +/- 262 N, n = 7) excluding the interligamentous and bone block fail
ure specimens. The ''inside-out'' technique averaged 100 N greater fix
ation strength than the ''outside-in'' technique. Statistical analysis
using two-sample Student's t-test showed no statistically significant
differences between group 1 and group 2. Both techniques demonstrate
comparable maximum load to failure in a bovine model tested at 50 cm/m
in.