A technique using a quartz crystal microbalance sensor coated with a t
hin culture medium film was developed and successfully applied to dete
rmine the number of Staphylococcus epidermidis (S. epidermidis) in the
range of 1 X 10(2)-4.1 x 10(7) cells ml(-1), based on a good linear r
elationship between the turning point time and the number of S. epider
midis. The technique is fast and accurate for detection of microorgani
sms due to the thin culture film and the sharp turning point of the re
sponse. The experimental conditions were discussed in detail.