MONITORING METHYLMERCURY DURING PREGNANCY - MATERNAL HAIR PREDICTS FETAL BRAIN EXPOSURE

Citation
E. Cernichiari et al., MONITORING METHYLMERCURY DURING PREGNANCY - MATERNAL HAIR PREDICTS FETAL BRAIN EXPOSURE, Neurotoxicology, 16(4), 1995, pp. 705-709
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy",Neurosciences
Journal title
ISSN journal
0161813X
Volume
16
Issue
4
Year of publication
1995
Pages
705 - 709
Database
ISI
SICI code
0161-813X(1995)16:4<705:MMDP-M>2.0.ZU;2-1
Abstract
Autopsy brains were obtained from infants dying from a variety of caus es within a few days of birth in a population exposed to methylmercury in fish. Infant and maternal blood and hair samples were also obtaine d. The concentration of total mercury in 6 major brain regions were hi ghly correlated with maternal hair levels. This correlation was confir med by a sequence of comparisons of maternal hair to maternal blood to infant blood and finally to infant brain. The results lend support to the use of maternal hair in assessing fetal exposure to methylmercury in fish-eating populations. (C) 1995 Intox Press, Inc.