ALPORTS-SYNDROME IN MONOZYGOTIC TWINS

Citation
Aym. Wang et al., ALPORTS-SYNDROME IN MONOZYGOTIC TWINS, American journal of kidney diseases, 27(2), 1996, pp. 267-269
Citations number
11
Categorie Soggetti
Urology & Nephrology
ISSN journal
02726386
Volume
27
Issue
2
Year of publication
1996
Pages
267 - 269
Database
ISI
SICI code
0272-6386(1996)27:2<267:AIMT>2.0.ZU;2-L
Abstract
Identical twins presented at the same time with renal failure, They al so recalled a simultaneous history of ''nephritis'' as early as the ag e of 6 years, Renal biopsies revealed variably thickened glomerular ba sement membranes with the lamellation and splitting characteristic of Alport's syndrome, Bilateral sensorineural deafness was demonstrated i n both twins on audiometric testing, A positive family history in the mother and one elder sister confirmed the diagnosis of Alport's syndro me, This is the first reported case of Alport's syndrome occurring in monozygotic twins. (C) 1996 by the National Kidney Foundation, Inc.