J. Luna et al., A FACTORIAL DESIGN TO DETERMINE THE EFFECTS OF SOME VARIABLES IN THE LONG-TERM STABILITY OF METHYLMERCURY STANDARD SOLUTIONS IN WATER, Fresenius' journal of analytical chemistry, 354(3), 1996, pp. 367-369
A factorial composite design has been employed for a rapid exploration
of the effect of some parameters on the stability of spiked methylmer
cury iodide solutions. The analysis has been performed by capillary ga
s chromatography with electron-capture detection. The results obtained
by the factorial and the univariate methods are in a good agreement.
Although, the factorial design does not allow a discrimination of the
significance among the same kind of factors, it greatly reduces the nu
mber of experiments when the different variables are investigated.