Da. Deliyannides et al., LITHIUM TREATMENT OF AGGRESSIVE-BEHAVIOR IN DEPRESSED, DRUG-DEPENDENTPATIENTS, The American journal on addictions, 5(1), 1996, pp. 87-90
Four non-bipolar I methadone-maintenance patients with irritability an
d aggressiveness were treated with lithium. Three had met criteria for
childhood conduct disorder and all four had adult antisocial features
. In each case there was a noticeable reduction in aggression and an i
mprovement in functioning. This finding suggests that there is a treat
able subgroup of drug-dependent patients with antisocial behavior.