THALIDOMIDE RESPONSIVE CHRONIC PULMONARY GVHD

Citation
Cj. Forsyth et al., THALIDOMIDE RESPONSIVE CHRONIC PULMONARY GVHD, Bone marrow transplantation, 17(2), 1996, pp. 291-293
Citations number
13
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
ISSN journal
02683369
Volume
17
Issue
2
Year of publication
1996
Pages
291 - 293
Database
ISI
SICI code
0268-3369(1996)17:2<291:TRCPG>2.0.ZU;2-7
Abstract
A 29-year-old male underwent allogeneic bone marrow transplantation fo r progressive multiple myeloma. His post-transplant course was complic ated by severe chronic pulmonary graft-versus-host disease (GVHD) resi stant to cyclosporin A, corticosteroids and azathioprine. The introduc tion of thalidomide resulted in a dramatic improvement in his lung fun ction which has been maintained even after cessation of thalidomide. H e remains well 40 months after transplantation.