Wr. Harding et al., DEATH OF A DOG ATTRIBUTED TO THE CYANOBACTERIAL (BLUE-GREEN-ALGAL) HEPATOTOXIN NODULARIN IN SOUTH-AFRICA, Journal of the South African Veterinary Medical Association, 66(4), 1995, pp. 256-259
A bull terrier died after drinking water at the margin of Zeekoevlei n
ear Cape Town. At the time, Zeekoevlei, a hypertrophic coastal lake, c
ontained a bloom of the cyanobacteria Nodularia spumigena and Microcys
tis aeruginosa. The circumstances of the incident, clinical signs of p
oisoning and histopathology, which mainly revealed extensive liver dam
age, were consistent with cyanobacterial poisoning. The cyanobacterial
bloom material contained 3,47 mu g mg(-1) dry weight of the pentapept
ide hepatotoxin nodularin. It is inferred that the dog died of cyanoba
cterial hepatotoxicosis due to the ingestion of nodularin.