THE CELLULAR-LOCALIZATION OF VASOACTIVE-INTESTINAL-PEPTIDE (VIP) IN THE MOUSE MEDIAN-EMINENCE BY IMMUNOELECTRON MICROSCOPY

Authors
DALCIK H CHEN IL DALCIK C PHELPS CJ
Citation
H. Dalcik et al., THE CELLULAR-LOCALIZATION OF VASOACTIVE-INTESTINAL-PEPTIDE (VIP) IN THE MOUSE MEDIAN-EMINENCE BY IMMUNOELECTRON MICROSCOPY, Acta histochemica, 98(1), 1996, pp. 53-59
Citations number
32
Categorie Soggetti
Cell Biology
Journal title
Acta histochemica → ACNP
ISSN journal
00651281
Volume
98
Issue
1
Year of publication
1996
Pages
53 - 59
Database
ISI
SICI code
0065-1281(1996)98:1<53:TCOV(I>2.0.ZU;2-L
Abstract
The aim of this study was to examine, by use of pre-embedding immunocy tochemistry, the ultrastructural localization of vasoactive intestinal peptide (VIP) immunoreactivity in the mouse median eminence. VIP immu noreactivity was observed in axonal profiles. The VIP-immunoreactive a xonal profiles were in close proximity to non-immunoreactive axonal pr ofiles that contained dense granular vesicles and clear vesicles and a lso to processes of tanycytes. VIP-immunoreactive terminals were obser ved in the proximity of the perivascular space and in the neuropil. Ou r results suggest that VIP-immunoreactive axon terminals may possibly interact with other non-immunoreactive axon terminals containing pepti de and/or other transmitters at the level of the median eminence or ma y be released to the portal vasculature thereby to effect anterior pit uitary cells.