PARANASAL SINUS DISEASE IN PATIENTS WITH CYSTIC-FIBROSIS

The enhanced understanding of the pathophysiology of cystic fibrosis ( CF) has advanced significantly the management of this disorder, result ing in both an increased longevity and an improved quality of life. Si nonasal disease is an important aspect of CF. The goal of this article is to provide a current synopsis of CF sinonasal disease with an emph asis on disease symptomatology, physical signs, characteristic radiogr aphic features, and outcome-based management options. When indicated, functional endoscopic sinus surgery has been shown to be a safe and ef fective treatment option for children with CF.