THE PREPARATION AND WITTIG CONDENSATIONS OF C-4 THIAZOLE PHOSPHONIUM METHYLIDES

Authors
WILLIAMS DR BROOKS DA MOORE JL STEWART AO
Citation
Dr. Williams et al., THE PREPARATION AND WITTIG CONDENSATIONS OF C-4 THIAZOLE PHOSPHONIUM METHYLIDES, Tetrahedron letters, 37(7), 1996, pp. 983-986
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
7
Year of publication
1996
Pages
983 - 986
Database
ISI
SICI code
0040-4039(1996)37:7<983:TPAWCO>2.0.ZU;2-U
Abstract
A modification of the Hantzsch thiazole synthesis is described which p roduces C-4 thiazolylmethyl phosphonium salts. Ylides are condensed wi th a variety of aldehydes to produce a series of 2,4-disubstituted thi azoles.